Alzheimer’s Isn’t That Simple: The theories keep coming but the cures remain elusive

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  1. tau is a protein most associated with the formation of microtubules that provide brain cells with nutrients. However, for unknown reasons, tau can collapse into tangles, thereby making the microtubules unable to provide the essential nutrients and eventually leading to cell death
  2. glucose metabolism via the brain’s mitochondria. “…a number of mitochondrial-dependent functions are found to be impaired during aging and AD.
  3. brain enhancers — a new approach to finding the genesis of brain degeneration in Alzheimer’s is proposed by a team led by Dr. Vivienne Labrie, who indicated that in the brain there are “genetic volume dials” called enhancers. These enhancers, which would normally be dormant in the adult brain, become overactive “in a suite of genes involved in Alzheimer’s pathology in brain cells, spurring the formation of plaques and tangles and reactivating the cell cycle in fully formed cells — a highly toxic combination.”

Dr. Farrell is a psychologist, WebMD consultant, SAG/AFTRA member, author, interested in film, writing & health. Website:

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